Microbrains for neurotoxicity testing, improved experimental design, and post-op severity assessment

May 2022 The papers behind the pod:  Wang, Q et al. (2022). Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity. ALTEX 39. https://doi.org/10.14573/altex.2112221 Reynolds P.S. (2022) Between two stools: preclinical research, reproducibility, and statistical design of experiments. BMC Res. Notes 15, 73.  https://doi.org/10.1186/s13104-022-05965-w Tappe-Theodor, A. et al. (2022) The “WWHow” Concept for Prospective Categorization of Post-operative Severity Assessment in Mice and Rats. Front. Vet. Sci. 9, 841431. https://doi.org/10.3389/fvets.2022.841431It’s the third Thursday of May, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce and refine the use of animals in research. This month, we’re bringing you a paper for each R. Follow this link for the full transcript: https://nc3rs.org.uk/3-minute-3rs-podcast-may-2022-transcript Hosted on Acast. See acast.com/privacy for more information.