The science of super longevity | Dr. Morgan Levine

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Science can’t stop aging, but it may be able to slow our epigenetic clocks. What if we could slow down the hands of our biological clocks? This question underpins much of the research of Morgan Levine, who leads a research team at the life science company Altos Labs. Levine investigates the fascinating intricacies of aging, recognizing that it doesn't happen at a uniform pace for everyone. Central to her exploration is the concept of epigenetics — the factors that influence gene activity without changing the DNA sequence. Levine focuses on DNA methylation, a significant epigenetic change that occurs with aging, and the development of models called "epigenetic clocks" that can be used to predict biological age. While she acknowledges that it might be possible to reverse aging at a cellular level, Levine clarifies that the ultimate goal is not to "cure" aging or death, but to delay disease onset and improve healthspan. ------------------------------------------------------------------------------------------------------------------------------------------------------- Chapters: 0:00 Fast agers & slow agers 1:25 The hallmarks of aging 1:59 What is the epigenetic clock? 3:05 Can we ‘Benjamin Button’ aging? 5:22 The holy grail for scientists Listen To This Next: Adam Grant's #1 phrase to unlock potential The science of super longevity Beat anxiety with the most addictive experience on Earth ------------------------------------------------------------------------------------------------------------------------------------------------------- Go Deeper with Big Think: ►Become a Big Think Member Get exclusive access to full interviews, early access to new releases, Big Think merch and more ►Get Big Think+ for Business Guide, inspire and accelerate leaders at all levels of your company with the biggest minds in business -------------------------------------------------------------------------------------------------------------------------------------------------------- About Big Think | Smarter Faster™ ► Big Think The leading source of expert-driven, educational content. With thousands of videos, featuring experts ranging from Bill Clinton to Bill Nye, Big Think helps you get smarter, faster by exploring the big ideas and core skills that define knowledge in the 21st century. Get Smarter, Faster. With Episodes From The Worlds Biggest Thinkers. Follow The Podcast And Turn On The Notifications Share This Episode If You Found It Valuable Leave A 5 Star Review... Learn more about your ad choices. Visit megaphone.fm/adchoices