Immunotherapy rechallenge in NSCLC

Expert: Alessandra Curioni-Fontecedro, University Hospital Zurich, Zurich, Switzerland Questions: 1.What's the accurate definition of immunotherapy rechallenge? 2.When we could rechallenge with immunotherapy after failure of previous I.O based therapy ? 3.There is any biomarkers to guide us in I.O rechallenge? 4.Which type of I..O could be used after failure of previous I.O? 5.what is the current trials that investigate this type of therapy?