COVIDcast - Tocilizumab

We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* Monoclonal antibodies have received significant attention over the past month and we previously podcasted on antibodies that target SARS-CoV-2. In this episode, we review several recent studies on a different "mab", tocilizumab,  which targets inflammation mediated by interleukin-6 that is overly ramped up.  We review: Stone et al  ( RCT) Hermine et al (RCT) Salvarani et al. (RCT) STOP-COVID (observational) Show notes (references/graphics): FOAMcast.org Thanks for listening, Lauren Westafer and Jeremy Faust