#86: Why you Can't Stay High Forever (Dr. Judith Grisel)

Neuroscientist Dr. Judith Grisel joins me to talk about mechanisms of addiction and why we can't stay high forever. We also discuss antiopioids, trends in drug use, tolerance, sensitization, how to talk to kids about drugs, and why youth is both the most common and most dangerous time to become addicted to drugs. Plus we cover how drugs work in the brain, how cannabinoids might actually be a neural marker of important memories, cocaine's action in the synapse, the neurology of opioid an...