#112 - Dr. John Lieurance: Melatonin The Miracle Molecule, Effective Supplementation, Circadian Rhythms, Inflammation Reduction, Tolerance & Toxicity, Mitochondrial Biogenesis, And More!

The Melanie Avalon Biohacking Podcast - A podcast by Melanie Avalon - Fridays

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/melatonin Go To melanieavalon.com/melatoninbook To Get The Free PDF Download And Use The Code Melanieavalon To Get 5% Off Any Products! 2:40 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:55 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon Stay Up To Date With All The News And Pre-Order Info About Melanie's New Serrapeptase Supplement At melanieavalon.com/serrapeptase! 5:20 - FOOD SENSE GUIDE: Get Melanie's App At Melanieavalon.com/foodsenseguide To Tackle Your Food Sensitivities! Food Sense Includes A Searchable Catalogue Of 300+ Foods, Revealing Their Gluten, FODMAP, Lectin, Histamine, Amine, Glutamate, Oxalate, Salicylate, Sulfite, And Thiol Status. Food Sense Also Includes Compound Overviews, Reactions To Look For, Lists Of Foods High And Low In Them, The Ability To Create Your Own Personal Lists, And More! 6:15 - BEAUTYCOUNTER: Non-Toxic Beauty Products Tested For Heavy Metals, Which Support Skin Health And Look Amazing! Shop At beautycounter.com/melanieavalon For Something Magical! For Exclusive Offers And Discounts, And More On The Science Of Skincare, Get On Melanie's Private Beautycounter Email List At melanieavalon.com/cleanbeauty! Find Your Perfect Beautycounter Products With Melanie's Quiz: melanieavalon.com/beautycounterquiz 11:20 - Dr. Lieurance's Personal Story 13:05 - Pain To Purpose 14:30 - Inflammation In All Disease 16:25 - The Signs In The Heart And The Brain 17:00 - Aerobic Glycolysis 18:00 - The Warburg Effect 18:45 - Cancer 21:00 - Genetics Related To Detox 23:55 - The Role Of Melatonin In Inflammation 27:45 - Are There Different Types Of Melatonin? 29:45 - Exogenous Melatonin 31:05 - Suppositories 32:30 - Melatonin Circadian Rhythms 34:00 - Using Red Light In The Evening 35:20 - Cellular Melatonin 36:25 - LEVELS CGM: Get Your Own Personal Continuous Glucose Monitor (CGM) To See How Your Blood Sugar Responds 24/7 To Your Food, Fasting, And Exercise! The Levels App Helps You Interpret The Data, To Take Charge Of Your Metabolic Health! Skip The 115K People Waitlist, At melanieavalon.com/levelscgm With The Code MelanieAvalon 38:35 - Heart Rate Variability 41:15 - Melatonin Dosing 41:45 - The Master Stress Hormone 43:00 - Intracellular Melatonin 44:25 - Melatonin And Sleepiness 45:30 - Wi-Fi Go To melanieavalon.com/melatoninbook To Get The Free PDF Download! 47:25 - The Lack Of Discussion Around Melatonin 49:25 - Microbiome Swarming 50:25 - The Rhythm In The Microbiome During Sleep 51:20 - Reduction Of HCL 51:40 - The Inverse Relationship Of Insulin & Melatonin 54:05 - A Short Fast Before Bed 54:30 - Chronotypes 55:35 - Insomniac Types 59:00 - The Half-Life Of Melatonin 1:00:05 - Typical Dosing 1:00:25 - High Exogenous Dosing Effect On Endogenous Production 1:01:35 - Toxicity & Tolerance 1:02:40 - Suppressive Efforts 1:03:45 - Vitamin D; OTC Regulation 1:04:05 - Blood Pressure Medication And Blood Pressure Lowering Effect 1:06:30 - LMNT: For Fasting Or Low-Carb Diets Electrolytes Are Key For Relieving Hunger, Cramps, Headaches, Tiredness, And Dizziness. With No Sugar, Artificial Ingredients, Coloring, And Only 2 Grams Of Carbs Per Packet Try LMNT For Complete And Total Hydration. For A Limited Time Go To drinklmnt.com/melanieavalon To Get A Sample Pack For Only The Price Of Shipping! 1:09:05 - Suppositorial Dosing 1:11:25 - Senescent Cells 1:13:35 - Fisetin & Polyphenols 1:14:10 - Mitophagy 1:14:55 - Mitochondrial Biogenesis 1:17:25 - Prevention Of Skin Burns 1:19:00 - Anti-Inflammatory Effect 1:20:10 - Using Binders For Detox 1:20:50 - Biotoxins & Mold 1:21:50 - Side Effects