Evaluation of benazepril in cats with heart disease | VETgirl Veterinary Continuing Education Podcasts

In today's VETgirl online veterinary continuing education podcast, we review the use of benazepril in cats with cardiac disease. Despite a wide variety of medications used to treat heart disease in cats, there is little prospective data to support a definitive benefit with use of any medication in cats with heart disease. Previous data has established a benefit for the use of angiotensin converting enzyme (ACE) inhibitors in humans and dogs with congestive heart failure. But what about cats? Activation of the renin-angiotensin-aldosterone system (RAAS) is a known phenomenon in cats with heart disease. So King et al (and I mean ALL) wanted to evaluate this in a study published in the Journal of Veterinary Internal Medicine in 2019 entitled Evaluation of benazepril in cats with heart disease in a prospective, randomized, blinded, placebo-controlled clinical trial. The authors of this study posited that benazepril, an ACE inhibitor, might provide benefit to cats with heart disease, regardless of type.