Dr. Karl Deisseroth: Understanding & Healing the Mind

Dr. Karl Deisseroth, MD, PhD, is a clinical psychiatrist and scientist who directs a bioengineering research laboratory at Stanford University School of Medicine. His work aims to understand and develop treatments for disorders of the mind such as depression, attention deficit disorders (ADHD & ADD), autism, schizophrenia, anxiety, eating disorders, borderline personality and obsessive-compulsive disorder. We discuss his experience treating his patients and his laboratory’s mission to find and develop cures for mental disease and tools for probing how the brain works.  For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Momentous:https://www.livemomentous.com/huberman Timestamps (00:00:00) Introduction (00:03:47) Sponsors: AG1, LMNT (00:07:41) Using Language to Understand the Mind (00:12:19) Blood Tests For Mental Disease (00:13:38) The Largest Challenges Facing Treatment of Mental Health (00:20:21) Predicting Depression & Suicide (00:22:47) Drugs That Work for Brain Illness (00:27:01) What Would A Cure For the Broken Mind Look Like? (00:32:23) Channelopsins: Tools For Understanding & Treating the Mind (00:39:10) Curing Blindness with Channelopsins (00:41:58) Why Karl Became a Scientist (00:47:10) Vagus Nerve In Depression (00:54:12) Challenges To Overcome for Treating Mental Illness with Channelopsins (00:58:34) Using the Dialogue with Patients to Guide Treatment (01:00:52) How Our Eyes Reveal Our Mental Health (01:06:04) Controlling Structures Deep In the Brain (01:08:23) The Most Effective Drugs Often Have the Most Side Effects (01:09:50) Do Psychiatrists Take the Drugs They Prescribe (01:14:15) Moving From Experimental Tools To Novel Treatments (01:16:00) Brain-Machine Interfaces & Neuralink (01:19:30) ADHD & Dr. Deissroth’s Approach To Focusing His Mind (01:26:36) How Dr. Deisseroth Balances A Career In Medicine, Science & Family (01:35:41) New Ways of Exploring Brains: CLARITY (01:38:49) What Is Special About the Human Brain? (01:46:03) Psychedelics (01:54:12) MDMA (01:57:15) Dr. Deisseroth’s New Book “Projections: A Story of Emotions” (01:59:42) Connecting with Dr. Deisseroth on Twitter Title Card Photo Credit: Mike Blabac Disclaimer

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Huberman Lab discusses neuroscience — how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Andrew Huberman, Ph.D., is a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. He has made numerous significant contributions to the fields of brain development, brain function and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills and cognitive functioning.  Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. His lab’s most recent work focuses on the influence of vision and respiration on human performance and brain states such as fear and courage. He also works on neural regeneration and directs a clinical trial to promote visual restoration in diseases that cause blindness. Huberman is also actively involved in developing tools now in use by the elite military in the U.S. and Canada, athletes, and technology industries to optimize performance in high stress environments, enhance neural plasticity, mitigate stress and optimize sleep.   Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals including Nature, Science and Cell and has been featured in TIME, BBC, Scientific American, Discover and other top media outlets.  In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 5 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.