Integrated Molecular Strategies in Combating Disease

New strategies in gene therapy are integrating multiple modern techniques to take on contemporary challenging diseases, such as solid-tumor cancers. Dr. Eric Ostertag of Poseida Therapeutics describes their transposon-based gene therapies that deliver useful gene replacements through biodegradable, tissue-targeted nanoparticles. This contrasts against the older gene therapy technologies that relied on viral delivery.  In addition, Poseida offers new approaches in CAR-T cell therapies, genetic adjustment of native immune cells to target cancers. These One-time treatments appear to be promising in treating a variety of cancers using innovative strategies.